The incidence of acute leukemia is increasing worldwide. In Ethiopia, in terms of incidence among all cancer cases, it ranks fourth and fifth in men and women respectively. Despite acute leukemia being this prevalent nationally and even a more concerning issue in Tikur Anbessa Specialized Hospital(TASH) the largest hemato-oncology center in the country, there have been only few studies done on this area so far. This study is important to have a contemporary data on the clinical presentation and outcome of acute leukemia patients and helps to put a light on gaps of acute leukemia care in for further detailed studies.