Assessing safety and ethical issues among participants in a herbal medicine phase І clinical trial: conducted in Addis Ababa Ethiopia: A Mixed Methods Research

Abstract

Ethics in the conduct of clinical research is mandatory to protect research participants. The goal of phase І clinical trial is to determine the maximum dose of the new medication that may be administered without the risk of serious side effects. Participants in most of phase І clinical trial have no direct benefit in participating in the trial but the amount of money provided for compensation can cause the participants to participate without being concerned to the risks the new drug may bring.